The titration constants of anserine, carnosine and some related compounds.

نویسندگان

  • A Deutsch
  • P Eggleton
چکیده

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منابع مشابه

Factors Affecting Anserine and Carnosine Levels in Skeletal Muscles of Various Animals

l. Analytical procedures for anserine, carnosine and related histidine compounds in skeletal muscles are given. 2. The anserineicarnosine ratio in the skeletal muscles of the rat increases with age, cortisone injection and lowered food intake, and in the guinea pig muscle with strenuous exercise. 3. The total anserine plus carnosine in leg muscles of the cat remain constant during long periods ...

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Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain.

Carnosine, homocarnosine, and anserine are present in high concentrations in the muscle and brain of many animals and humans. However, their exact function is not clear. The antioxidant activity of these compounds has been examined by testing their peroxyl radical-trapping ability at physiological concentrations. Carnosine, homocarnosine, anserine, and other histidine derivatives all showed ant...

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Carnosine and Anserine in Mammalian Skeletal Muscle *

Two imidazole derivatives, carnosine and anserine, have been isolated from vertebrate skeletal muscle. Carnosine may be readily obtained from the ox (l), horse (2), pig (3), etc. Anserine, a methyl carnosine, has been isolated from birds, a reptile (4), fish (5), and certain mammals (6). The presence of the two compounds in muscles from the same animal has been adequately demonstrated only once...

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Carnosine, homocarnosine and anserine: could they act as antioxidants in vivo?

Carnosine, homocarnosine and anserine have been proposed to act as antioxidants in vivo. Our studies show that all three compounds are good scavengers of the hydroxyl radical (.OH) but that none of them can react with superoxide radical, hydrogen peroxide or hypochlorous acid at biologically significant rates. None of them can bind iron ions in ways that interfere with 'site-specific' iron-depe...

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Effect of carnosine and related compounds on the inactivation of human Cu,Zn-superoxide dismutase by modification of fructose and glycolaldehyde.

Glycolaldehyde, an intermediate of the Maillard reaction, and fructose, which is mainly derived from the polyol pathway, rapidly inactivate human Cu,Zn-superoxide dismutase (SOD) at the physiological concentration. We employed this inactivation with these carbonyl compounds as a model glycation reaction to investigate whether carnosine and its related compounds could protect the enzyme from ina...

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عنوان ژورنال:
  • The Biochemical journal

دوره 32 2  شماره 

صفحات  -

تاریخ انتشار 1938